Supplementary Materials

Supplementary Material for:

Filaggrin inhibits generation of CD1a neolipid antigens by house dust mite–derived phospholipase

Rachael Jarrett, Mariolina Salio, Antonia Lloyd-Lavery, Sumithra Subramaniam, Elvire Bourgeois, Charles Archer, Ka Lun Cheung, Clare Hardman, David Chandler, Maryam Salimi, Danuta Gutowska-Owsiak, Jorge Bernardino de la Serna, Padraic G. Fallon, Helen Jolin, Andrew Mckenzie, Andrzej Dziembowski, Ewa Izabela Podobas, Wojciech Bal, David Johnson, D. Branch Moody, Vincenzo Cerundolo, Graham Ogg*

*Corresponding author. E-mail: graham.ogg{at}

Published 10 February 2016, Sci. Transl. Med. 8, 325ra18 (2016)
DOI: 10.1126/scitranslmed.aad6833

This PDF file includes:

  • Fig. S1. mDC and LC-like cell expression of CD1a and langerin.
  • Fig. S2. HDM-responsive CD1a-reactive T cells can produce IFNγ and/or IL-13 and are not enriched in patients with psoriasis.
  • Fig. S3. HDM-responsive CD1a-reactive T cells associate with FLG mutations.
  • Fig. S4. Viral-specific T cell responses in the presence of manoalide and filaggrin.
  • Table S1. Source data.

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