Supplementary Materials

Supplementary Material for:

Development of a therapeutic monoclonal antibody that targets secreted fatty acid–binding protein aP2 to treat type 2 diabetes

M. Furkan Burak, Karen E. Inouye, Ariel White, Alexandra Lee, Gurol Tuncman, Ediz S. Calay, Motohiro Sekiya, Amir Tirosh, Kosei Eguchi, Gabriel Birrane, Daniel Lightwood, Louise Howells, Geofrey Odede, Hanna Hailu, Shauna West, Rachel Garlish, Helen Neale, Carl Doyle, Adrian Moore, Gökhan S. Hotamisligil*

*Corresponding author. E-mail: ghotamis{at}hsph.harvard.edu

Published 23 December 2015, Sci. Transl. Med. 7, 319ra205 (2015)
DOI: 10.1126/scitranslmed.aac6336

This PDF file includes:

  • Fig. S1. Screening cohort.
  • Fig. S2. Effect of antibody on lipid binding to aP2.
  • Fig. S3. Hyperinsulinemic-euglycemic clamp of HFD mice treated with CA33.

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