Supplementary Materials

Supplementary Material for:

Cell-selective arrhythmia ablation for photomodulation of heart rhythm

Uma Mahesh R. Avula, Hyung Ki Yoon, Chang H. Lee, Kuljeet Kaur, Rafael J. Ramirez, Yoshio Takemoto, Steven R. Ennis, Fred Morady, Todd Herron, Omer Berenfeld, Raoul Kopelman,* Jérôme Kalifa*

*Corresponding author. E-mail: kalifaj{at}med.umich.edu (J.K.); kopelman{at}umich.edu (R.K.)

Published 28 October 2015, Sci. Transl. Med. 7, 311ra172 (2015)
DOI: 10.1126/scitranslmed.aab3665

This PDF file includes:

  • Methods
  • Fig. S1. Characteristics of CTP-Ce6-PEG nanoparticle.
  • Fig. S2. Nontargeted control experiments in vitro.
  • Fig. S3. Targeted and nontargeted PDT in a coculture of human cardiac myocytes and fibroblasts.
  • Fig. S4. Photoablated lesion depth analysis.
  • Fig. S5. Thermal imaging during PDT ablation.
  • References (3641)
  • Legends for movies S1 to S3

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Other Supplementary Material for this manuscript includes the following:

  • Movie S1. (.avi format). Optical mapping of a rat heart 3 days after photoablation.
  • Movie S2. (.avi format). Optical mapping of the sheep right atrial free wall.
  • Movie S3. (.avi format). Optical mapping of the sheep right ventricle.