Supplementary Materials

Supplementary Material for:

Mortality factor 4 like 1 protein mediates epithelial cell death in a mouse model of pneumonia

Chunbin Zou,* Jin Li, Sheng Xiong, Yan Chen, Qin Wu, Xiuying Li, Nathaniel M. Weathington, SeungHye Han, Courtney Snavely, Bill B. Chen, Rama K. Mallampalli*

*Corresponding author. E-mail: mallampallirk{at}upmc.edu (R.K.M.); zouc{at}upmc.edu (C.Z.)

Published 28 October 2015, Sci. Transl. Med. 7, 311ra171 (2015)
DOI: 10.1126/scitranslmed.aac7793

This PDF file includes:

  • Materials and Methods
  • Fig. S1. Endotoxin and P. aeruginosa increase Morf4l1 protein levels posttranslationally in lung cells.
  • Fig. S2. Bacterial pathogens trigger Morf4l1 acetylation.
  • Fig. S3. Effect of Morf4l1 depletion or antagonism on bacterial loads.
  • Fig. S4. Effect of Morf4l1 depletion or antagonism on the Fas cell death pathway.
  • Fig. S5. Morf4l1 mediates cell death in pneumonia.

[Download PDF]