Supplementary Materials

Supplementary Material for:

ST2 blockade reduces sST2-producing T cells while maintaining protective mST2-expressing T cells during graft-versus-host disease

Jilu Zhang, Abdulraouf M. Ramadan, Brad Griesenauer, Wei Li, Matthew J. Turner, Chen Liu, Reuben Kapur, Helmut Hanenberg, Bruce R. Blazar, Isao Tawara, Sophie Paczesny*

*Corresponding author. E-mail: sophpacz{at}

Published 7 October 2015, Sci. Transl. Med. 7, 308ra160 (2015)
DOI: 10.1126/scitranslmed.aab0166

This PDF file includes:

  • Materials and Methods
  • Fig. S1. Six dose ST2 blockade and GVHD.
  • Fig. S2. Host ST2 deficiency and GVHD.
  • Fig. S3. mST2 expression on T cell subsets.
  • Fig. S4. Antigen-presenting cells and GVHD.
  • Fig. S5. MLN dendritic cells and GVHD.
  • Fig. S6. IL-33 administration and GVHD.
  • Fig. S7. Immune complex depletion.
  • Fig. S8. ST2 deficiency in Tconv cells and GVHD.
  • Fig. S9. Unmodified blots.
  • Fig. S10. Gating strategies of flow cytometric analysis for Fig. 3.
  • Fig. S11. Gating strategies of flow cytometric analysis for Fig. 4E.
  • Table S1. P values for Fig. 1.
  • Table S2. P values for Fig. 2.
  • Table S3. P values for figs. S1, S2, and S8.
  • Table S4. Antibodies for flow cytometry.

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Other Supplementary Material for this manuscript includes the following:

  • Additional Data Tables (separate file)

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