Supplementary Materials

Supplementary Material for:

JC polyomavirus mutants escape antibody-mediated neutralization

Upasana Ray, Paola Cinque, Simonetta Gerevini, Valeria Longo, Adriano Lazzarin, Sven Schippling, Roland Martin, Christopher B. Buck,* Diana V. Pastrana*

*Corresponding author. E-mail: buckc{at}mail.nih.gov (C.B.B.); pastrand{at}mail.nih.gov (D.V.P.)

Published 23 September 2015, Sci. Transl. Med. 7, 306ra151 (2015)
DOI: 10.1126/scitranslmed.aab1720

This PDF file includes:

  • Text
  • Fig. S1. Transducibility of various cell lines.
  • Fig. S2. An example of luminometry results for a pilot JCV neutralization assay using ART cells.
  • Fig. S3. Neutralization assay validation.
  • Fig. S4. PML patient neutralization serology (an expansion of Fig. 2).
  • Fig. S5. Serological analysis of mice after a booster dose of JCV VLPs.
  • Fig. S6. JCV-neutralizing titers after vaccination of PML patient 5228 (an alternative version of Fig. 4).
  • Table S1. Characteristics of JCV pseudovirus stocks.
  • Table S2. Patient characteristics.
  • Table S3. PML patient neutralization serology (source data).
  • Table S4. Neutralization serology of patient 5228 (source data).
  • Table S5. Viremia of patient 5228 (source data).
  • References (4048)

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