Supplementary Materials

Supplementary Material for:

Transglutaminase 4 as a prostate autoantigen in male subfertility

Nils Landegren,* Donald Sharon, Anthony K. Shum, Imran S. Khan, Kayla J. Fasano, Åsa Hallgren, Caroline Kampf, Eva Freyhult, Brita Ardesjö-Lundgren, Mohammad Alimohammadi, Sandra Rathsman, Jonas F. Ludvigsson, Dan Lundh, Ruben Motrich, Virginia Rivero, Lawrence Fong, Aleksander Giwercman, Jan Gustafsson, Jaakko Perheentupa, Eystein S. Husebye, Mark S. Anderson, Michael Snyder, Olle Kämpe

*Corresponding author. E-mail: nils.landegren{at}ki.se

Published 17 June 2015, Sci. Transl. Med. 7, 292ra101 (2015)
DOI: 10.1126/scitranslmed.aaa9186

This PDF file includes:

  • Fig. S1. Confirmation of TGM4 autoantibodies using an RLBA.
  • Fig. S2. TGM4 mRNA expression in multiple human tissues, detected by digital droplet PCR.
  • Fig. S3. TGM4 protein expression in multiple human tissues, detected by immunohistochemistry.
  • Fig. S4. TGM4 protein expression in multiple human tissues, detected by immuno-rolling circle amplification.
  • Fig. S5. Male Aire-deficient NOD mice display TGM4 autoantibodies.
  • Fig. S6. Male wild-type NOD mice display TGM4 autoantibodies.
  • Table S1. Characterization of APS1 patients.
  • Table S2. Autoantibodies in young male APS1 patients.
  • Table S3. TGM4 autoantibodies first appear during pubertal age.
  • Table S4. mRNA expression in mouse prostates.
  • Table S5. TGM4 mRNA expression in mTECs.

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