Supplementary Materials

Supplementary Material for:

Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against Plasmodium falciparum infection in Kenyan adults

Caroline Ogwang, Domtila Kimani, Nick J. Edwards, Rachel Roberts, Jedidah Mwacharo, Georgina Bowyer, Carly Bliss, Susanne H. Hodgson, Patricia Njuguna, Nicola K. Viebig, Alfredo Nicosia, Evelyn Gitau, Sandy Douglas, Joe Illingworth, Kevin Marsh, Alison Lawrie, Egeruan B. Imoukhuede, Katie Ewer, Britta C. Urban, Adrian V. S. Hill, Philip Bejon,* the MVVC group

*Corresponding author. E-mail: pbejon{at}

Published 6 May 2015, Sci. Transl. Med. 7, 286re5 (2015)
DOI: 10.1126/scitranslmed.aaa2373

This PDF file includes:

  • Methods
  • Fig. S1. CONSORT flow diagram.
  • Fig. S2. Seasonal malaria.
  • Table S1. Postvaccination solicited adverse events.
  • Table S2. Listing of unsolicited adverse events identified within 30 days after vaccination.
  • Table S3. Frequency of out-of-range laboratory results for safety assessments by vaccination group.
  • Table S4. Median and IQR of laboratory results for safety assessments by vaccination group.
  • Table S5. Line listing of laboratory abnormalities seen after vaccination.
  • Table S6. Geometric mean immunological responses by vaccination allocation and by study visit.
  • Table S7. Criteria used to determine grade of solicited local adverse events.
  • Table S8. Criteria used to assessment of causality of adverse events.
  • Table S9. Peptide pooling scheme used for ELISPOT assays.
  • Table S10. SNPs typed in Sequenom assay.

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