Supplementary Materials

Supplementary Material for:

Interferon-λ restricts West Nile virus neuroinvasion by tightening the blood-brain barrier

Helen M. Lazear, Brian P. Daniels, Amelia K. Pinto, Albert C. Huang, Sarah C. Vick, Sean E. Doyle, Michael Gale Jr., Robyn S. Klein,* Michael S. Diamond*

*Corresponding author. E-mail: diamond{at}borcim.wustl.edu (M.S.D.); rklein{at}dom.wustl.edu (R.S.K.);

Published 22 April 2015, Sci. Transl. Med. 7, 284ra59 (2015)
DOI: 10.1126/scitranslmed.aaa4304

This PDF file includes:

  • Fig. S1. Serum antibody responses in wild-type and Ifnlr1−/− mice.
    Fig. S2. Serum type I IFN activity in wild-type and Ifnlr1−/− mice.
    Fig. S3. ISG induction in BMECs.
    Table S1. Transcriptional profiling of DCs treated with IFN-β or IFN-λ.
    Table S2. Serum cytokines after WNV infection.
    Table S3. Primer and probe sequences used for qRT-PCR.

[Download PDF]

Other Supplementary Material for this manuscript includes the following:

  • Primary data tables. (Excel)

[Download Primary data tables]