Supplementary Materials

Supplementary Material for:

Long-lasting stem cell–like memory CD8+ T cells with a naïve-like profile upon yellow fever vaccination

Silvia A. Fuertes Marraco, Charlotte Soneson, Laurène Cagnon, Philippe O. Gannon, Mathilde Allard, Samia Abed Maillard, Nicole Montandon, Nathalie Rufer, Sophie Waldvogel, Mauro Delorenzi, Daniel E. Speiser*

*Corresponding author. E-mail: doc{at}

Published 8 April 2015, Sci. Transl. Med. 7, 282ra48 (2015)
DOI: 10.1126/scitranslmed.aaa3700

This PDF file includes:

  • Fig. S1. Influence of interdonor and age-related variability and its normalization for the study of A2/NS4b+ CD8+ T cell subsets.
  • Fig. S2. Data complementary to Fig. 3.
  • Fig. S3. Analyses of CD8+ T cells specific for YF epitopes alternative to the HLA-A*02–restricted NS4b.
  • Fig. S4. Data complementary to Fig. 5.
  • Fig. S5. Data complementary to Fig. 6.
  • Fig. S6. Cytokine production by NS4b-specific CD8+ T cell subsets in comparison to the reference subsets in total CD8+ T cells.
  • Table S1. Summary of the cohort of YF-17D vaccines.
  • Table S2. Main genes contributing to PC1.
  • Legend for table S3
  • Table S4. Tetramers and antibodies used for flow cytometry analyses.

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Other Supplementary Material for this manuscript includes the following:

  • Table S3 (Microsoft Excel format). Differentially expressed genes comparing naïve-like A2/NS4b+ CD8+ T cells to the other four subsets listed (Excel).

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