Supplementary Materials

Supplementary Material for:

Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAFV600E melanoma

Siwen Hu-Lieskovan, Stephen Mok, Blanca Homet Moreno, Jennifer Tsoi, Lidia Robert, Lucas Goedert, Elaine M. Pinheiro, Richard C. Koya, Thomas G. Graeber, BegoƱa Comin-Anduix, Antoni Ribas*

*Corresponding author. E-mail: aribas{at}

Published 18 March 2015, Sci. Transl. Med. 7, 279ra41 (2015)
DOI: 10.1126/scitranslmed.aaa4691

This PDF file includes:

  • Fig. S1. In vitro study of effects of dabrafenib and trametinib on effector T cell and gating strategies.
  • Fig. S2. Microarray analysis quality control, all gene clustering, and expression of interested genes.
  • Fig. S3. Source data of Western blots in Fig. 1A.

[Download PDF]

Other Supplementary Material for this manuscript includes the following:

  • Table S1 (Microsoft Excel format). Immune A genes.
  • Table S2 (Microsoft Excel format). Immune B genes.
  • Table S3 (Microsoft Excel format). Immune C genes.
  • Table S4 (Microsoft Excel format). Source data of tumor growth curves in Figs. 1B, 1D, and 6D.

[Download Tables S1 to S4]