Supplementary Materials

Supplementary Material for:

Human skin is protected by four functionally and phenotypically discrete populations of resident and recirculating memory T cells

Rei Watanabe, Ahmed Gehad, Chao Yang, Laura L. Scott, Jessica E. Teague, Christoph Schlapbach, Christopher P. Elco, Victor Huang, Tiago R. Matos, Thomas S. Kupper, Rachael A. Clark*

*Corresponding author. E-mail: rclark1{at}partners.org

Published 18 March 2015, Sci. Transl. Med. 7, 279ra39 (2015)
DOI: 10.1126/scitranslmed.3010302

This PDF file includes:

  • Fig. S1. T cell infiltration in human-engrafted mice.
  • Fig. S2. Epidermal T cells lost functional activity and underwent apoptosis after removal from the skin microenvironment.
  • Fig. S3. A subset of CCR7+ T cells in human dermis express CD69, and a small subset of skin TRM coexpress L-selectin.
  • Fig. S4. Gating strategy and representative histograms for the data displayed in Fig. 6C.
  • Fig. S5. Tables of primary data for Figs. 1 to 8.
  • Fig. S6. Isotype controls for immunofluorescence images for Figs. 1, 3, and 6.
  • Fig. S7. Gating strategy and isotype controls for flow cytometry studies shown in Figs. 1 to 8.

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