Supplementary Materials

Supplementary Material for:

The gut microbiota influences blood-brain barrier permeability in mice

Viorica Braniste,* Maha Al-Asmakh, Czeslawa Kowal, Farhana Anuar, Afrouz Abbaspour, Miklós Tóth, Agata Korecka, Nadja Bakocevic, Lai Guan Ng, Parag Kundu, Balázs Gulyás, Christer Halldin, Kjell Hultenby, Harriet Nilsson, Hans Hebert, Bruce T. Volpe, Betty Diamond, Sven Pettersson*

*Corresponding author. E-mail: viorica.braniste{at} (V.B.); sven.pettersson{at} (S.P.)

Published 19 November 2014, Sci. Transl. Med. 6, 263ra158 (2014)
DOI: 10.1126/scitranslmed.3009759

This PDF file includes:

  • Material and Methods
  • Fig. S1. Expression of tight junction proteins in the brains of germ- and pathogen-free adult female mice.
  • Fig. S2. Electron micrographs showing different tight junction structure (white arrows) in the brains of germ-free adult mice.
  • Fig. S3. The effect of oral treatment with the bacterial metabolite sodium butyrate or monocolonization with C. tyrobutyricum on histone acetylation in extracts of mouse brain frontal cortex.

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