Supplementary Material for:

Prediction of resistance development against drug combinations by collateral responses to component drugs

Christian Munck, Heidi K. Gumpert, Annika I. Nilsson Wallin, Harris H. Wang, Morten O. A. Sommer*

*Corresponding author. E-mail: msom{at}bio.dtu.dk

Published 12 November 2014, Sci. Transl. Med. 6, 262ra156 (2014)
DOI: 10.1126/scitranslmed.3009940

This PDF file includes:

• Fig. S1. Fold increase in drug tolerance during evolution experiment.
• Fig. S2. IC₉₀ dose-response curves.
• Fig. S3. Correlation between IC₅₀ or MIC, and IC₉₀-based measurements.
• Fig. S4. Alternative correlation between FICI and evolution of resistance.
• Fig. S5. Competition between wild-type ΔlacZ and mutant.
• Table S1. Raw OD₆₀₀ readings.
• Table S2. Sequencing coverage.
• Table S3. Individual SNPs and INDELs.
• Table S4. Oligos for MAGE and qPCR primers.
• Reference (76)

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