Supplementary Materials

Supplementary Material for:

Targeting latent TGFβ release in muscular dystrophy

Ermelinda Ceco, Sasha Bogdanovich, Brandon Gardner, Tamari Miller, Adam DeJesus, Judy U. Earley, Michele Hadhazy, Lucas R. Smith, Elisabeth R. Barton, Jeffery D. Molkentin, Elizabeth M. McNally*

*Corresponding author. E-mail: elizabeth.mcnally{at}

Published 22 October 2014, Sci. Transl. Med. 6, 259ra144 (2014)
DOI: 10.1126/scitranslmed.3010018

This PDF file includes:

  • Fig. S1. LTBP4 cleavage is specifically blocked by the anti-PRR antibody.
  • Fig. S2. The BAC transgene does not alter membrane leak and fibrosis.
  • Fig. S3. Human LTBP4 (hLTBP4) expression intensifies mdx muscle pathology.
  • Fig. S4. Multiple muscles are worsened by the hLTBP4 transgene in the mdx mouse.
  • Fig. S5. Increased macrophage infiltration in hLTBP4/mdx muscle.

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