Supplementary Materials

Supplementary Material for:

Treatment of heterotopic ossification through remote ATP hydrolysis

Jonathan R. Peterson, Sara De La Rosa, Oluwatobi Eboda, Katherine E. Cilwa, Shailesh Agarwal, Steven R. Buchman, Paul S. Cederna, Chuanwu Xi, Michael D. Morris, David N. Herndon, Wenzhong Xiao, Ronald G. Tompkins, Paul H. Krebsbach, Stewart C. Wang, Benjamin Levi*

*Corresponding author. E-mail: blevi{at}

Published 24 September 2014, Sci. Transl. Med. 6, 255ra132 (2014)
DOI: 10.1126/scitranslmed.3008810

This PDF file includes:

  • Fig. S1. Burn injury increases inflammatory response globally and at distant tenotomy site.
  • Fig. S2. LDN-193189 did not reduce bone mineral density.
  • Fig. S3. Apyrase treatment did not reduce bone mineral density.
  • Fig. S4. Combination treatment with apyrase and LDN-193189 markedly inhibited HO formation.
  • Fig. S5. Global anti-inflammatory treatment reduced HO formation.
  • Table S1. Microarray data.
  • Table S2. Primer sequences for qRT-PCR.
  • Table S3. Data used in figures.

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