Supplementary Materials

Supplementary Material for:

The HMGB1-RAGE axis mediates traumatic brain injury–induced pulmonary dysfunction in lung transplantation

Daniel J. Weber, Adam S. A. Gracon, Matthew S. Ripsch, Amanda J. Fisher, Bo M. Cheon, Pankita H. Pandya, Ragini Vittal, Maegan L. Capitano, Youngsook Kim, Yohance M. Allette, Amanda A. Riley, Brian P. McCarthy, Paul R. Territo, Gary D. Hutchins, Hal E. Broxmeyer, George E. Sandusky, Fletcher A. White, David S. Wilkes*

*Corresponding author. E-mail:

Published 3 September 2014, Sci. Transl. Med. 6, 252ra124 (2014)
DOI: 10.1126/scitranslmed.3009443

This PDF file includes:

  • Materials and Methods
  • Fig. S1. MPO levels in sham and TBI mice.
  • Fig. S2. Presence of activated caspase-3 in pulmonary tissue after TBI.
  • Fig. S3. RAGE is present in the lung but not in other tissues of C57BL/6 mice.
  • Fig. S4. IHC staining against HMGB1 in lungs of sham and TBI mice.
  • Fig. S5. HMGB1 staining in normal and injured cortical tissue.
  • Fig. S6. Airway resistance values after TBI.
  • Fig. S7. Cardiac output after TBI.
  • References (5963)

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