Supplementary Materials

Supplementary Material for:

Aldehyde dehydrogenase-2 regulates nociception in rodent models of acute inflammatory pain

Vanessa O. Zambelli, Eric R. Gross, Che-Hong Chen, Vanessa P. Gutierrez, Yara Cury, Daria Mochly-Rosen*

*Corresponding author. E-mail:

Published 27 August 2014, Sci. Transl. Med. 6, 251ra118 (2014)
DOI: 10.1126/scitranslmed.3009539

This PDF file includes:

  • Fig. S1. Scheme for generation of ALDH2*2 (E487K) knock-in mice.
  • Fig. S2. Rotarod data.
  • Fig. S3. ALDH2 protein level in mouse paw and additional nociceptive data.
  • Fig. S4. Nociceptive testing.
  • Fig. S5. Neutrophil elastase protein levels.
  • Fig. S6. Formalin-induced pain model.
  • Table S1. ALDH activation by Alda-1.

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