Supplementary Materials

Supplementary Material for:

Plasmodium falciparum transmission stages accumulate in the human bone marrow

Regina Joice, Sandra K. Nilsson, Jacqui Montgomery, Selasi Dankwa, Elizabeth Egan, Belinda Morahan, Karl B. Seydel, Lucia Bertuccini, Pietro Alano, Kim C. Williamson, Manoj T. Duraisingh, Terrie E. Taylor, Danny A. Milner, Matthias Marti*

*Corresponding author. E-mail:

Published 9 July 2014, Sci. Transl. Med. 6, 244re5 (2014)
DOI: 10.1126/scitranslmed.3008882

This PDF file includes:

  • Materials and methods
  • Fig. S1. Representative pLDH and Pfs16 labeling across tissues.
  • Fig. S2. Stage specificity of antibodies by immunohistochemistry.
  • Fig. S3. Morphology and dimensions of parasites by immunohistochemistry.
  • Fig. S4. Development of qRT-PCR assay.
  • Fig. S5. RNA quality from brain and bone marrow tissue samples.
  • Fig. S6. Invasion and development of gametocytes in erythroid precursor cells.
  • Fig. S7. Proposed models for P. falciparum gametocyte development.
  • Fig. S8. Flow chart of samples used in Figs. 1 to 3.
  • Table S1. Gametocyte fraction in bone marrow versus clinical parameters.
  • Table S2. Primer pairs used in qRT-PCR assay.
  • References (2629)

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