Supplementary Materials

Supplementary Material for:

Intraindividual genome expression analysis reveals a specific molecular signature of psoriasis and eczema

Maria Quaranta, Bettina Knapp, Natalie Garzorz, Martina Mattii, Venu Pullabhatla, Davide Pennino, Christian Andres, Claudia Traidl-Hoffmann, Andrea Cavani, Fabian J. Theis, Johannes Ring, Carsten B. Schmidt-Weber, Stefanie Eyerich, Kilian Eyerich*

*Corresponding author. E-mail: kilian.eyerich@lrz.tum.de

Published 9 July 2014, Sci. Transl. Med. 6, 244ra90 (2014)
DOI: 10.1126/scitranslmed.3008946

This PDF file includes:

  • Fig. S1. Clustering analysis of significantly regulated genes results in grouping of the diseases.
  • Fig. S2. Identification of two false-positive patch test results in the induced eczema cohort based on gene regulation consistency.
  • Fig. S3. Clinical and histological presentation of a patient initially misdiagnosed as psoriasis as detected by the disease classifier.
  • Fig. S4. Flow chart of patient cohorts used for microarray data, classifier training, and classifier testing.
  • Table S1. Top hit list of genes regulated in both psoriasis and eczema as well as of exclusively regulated genes.
  • Table S2. Raw data of pathway analysis in psoriasis and eczema as shown in Fig. 3.
  • Table S3. Top hit list of genes regulated both in eczema subtypes and exclusively in induced or naturally occurring eczema.
  • Table S4. Raw data of pathway analysis in eczema subtypes as shown in Fig. 4.
  • Table S5. Identification of two false-positive patch test results in the induced eczema cohort based on gene regulation consistency.
  • Table S6. Primers used for validation of disease classifier.
  • Table S7. Probabilities of the patients in the independent test cohort for the diagnosis of psoriasis or eczema according to the disease classifier (n = 34 plus unclear case as indicated below).

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