Supplementary Materials

Supplementary Material for:

An Antidepressant Decreases CSF Aβ Production in Healthy Individuals and in Transgenic AD Mice

Yvette I. Sheline,* Tim West, Kevin Yarasheski, Robert Swarm, Mateusz S. Jasielec, Jonathan R. Fisher, Whitney D. Ficker, Ping Yan, Chengjie Xiong, Christine Frederiksen, Monica V. Grzelak, Robert Chott, Randall J. Bateman, John C. Morris, Mark A. Mintun, Jin-Moo Lee, John R. Cirrito

*Corresponding author. E-mail: sheline{at}

Published 14 May 2014, Sci. Transl. Med. 6, 236re4 (2014)
DOI: 10.1126/scitranslmed.3008169

This PDF file includes:

  • Fig. S1. Plaque load in aged APP/PS1 mice dose response.
  • Fig. S2. CSF Aβ tracer-to-tracee ratio did not differ between citalopram and placebo.

[Download PDF]