Supplementary Materials

Supplementary Material for:

T Cell Costimulation Molecules CD80/86 Inhibit Osteoclast Differentiation by Inducing the IDO/Tryptophan Pathway

Aline Bozec, Mario M. Zaiss, Rosebeth Kagwiria, Reinhard Voll, Manfred Rauh, Zhu Chen, Sandra Mueller-Schmucker, Richard A. Kroczek, Lucie Heinzerling, Muriel Moser, Andrew L. Mellor, Jean-Pierre David, Georg Schett*

*Corresponding author. E-mail:

Published 7 May 2014, Sci. Transl. Med. 6, 235ra60 (2014)
DOI: 10.1126/scitranslmed.3007764

This PDF file includes:

  • Fig. S1. No difference in osteoblast-related bone parameters between wild-type mice and CD80/86−/− mice.
  • Fig. S2. No difference in osteoclast-related bone parameters between wild-type mice and costimulation mutants.
  • Fig. S3. Effects of CTLA-4 on osteoclast precursor apoptosis.
  • Fig. S4. Proliferation of osteoclast precursors.
  • Fig. S5. Osteoclast precursor numbers in CD80/86−/− mice.

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