Supplementary Materials

Supplementary Material for:

FibronectinEDA Promotes Chronic Cutaneous Fibrosis Through Toll-Like Receptor Signaling

Swati Bhattacharyya,* Zenshiro Tamaki, Wenxia Wang, Monique Hinchcliff, Paul Hoover, Spiro Getsios, Eric S. White, John Varga*

*Corresponding author. E-mail: s-bhattacharyya@northwestern.edu (S.B.); j-varga@northwestern.edu (J.V.)

Published 16 April 2014, Sci. Transl. Med. 6, 232ra50 (2014)
DOI: 10.1126/scitranslmed.3008264

This PDF file includes:

  • Fig. S1. FnEDA expression is elevated in bleomycin-treated mice.
  • Fig. S2. Attenuated Smad2 activation and elastin accumulation in FnEDA-null mice.
  • Fig. S3. FnEDA elicits TLR4-dependent proinflammatory and fibrotic responses.
  • Fig. S4. miR29 mediates fibroblast responses elicited by FnEDA.
  • Table S1. Primers for real-time qPCR.
  • Table S2. Comparison of patients with low versus high serum levels of FnEDA.

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