Supplementary Materials

Supplementary Material for:

Functional Network Pipeline Reveals Genetic Determinants Associated with in Situ Lymphocyte Proliferation and Survival of Cancer Patients

Bernhard Mlecnik, Gabriela Bindea, Helen K. Angell, Maria Stella Sasso, Anna C. Obenauf, Tessa Fredriksen, Lucie Lafontaine, Amelie M. Bilocq, Amos Kirilovsky, Marie Tosolini, Maximilian Waldner, Anne Berger, Wolf Herman Fridman, Arash Rafii, Viia Valge-Archer, Franck Pagès, Michael R. Speicher, Jérôme Galon*

*Corresponding author. E-mail:

Published 19 March 2014, Sci. Transl. Med. 6, 228ra37 (2014)
DOI: 10.1126/scitranslmed.3007240

This PDF file includes:

  • Fig. S1. Cell types expressing IL15.
  • Fig. S2. Schematic representation of IL15 impact on immune cell proliferation within tumors.
  • Table S1. Cytokines investigated in CRC: Families and the chromosomal location.
  • Table S2. Genomic alterations of cytokines in CRC.
  • Table S3. Genomic alterations of cytokines in relation with metastasis of CRC patients.
  • Table S4. The impact of genomic alterations of cytokines on the gene expression and the CRC patient disease-free survival.
  • Table S5. Clinical characteristics of the cohorts investigated.

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