Supplementary Materials

Supplementary Material for:

CXCL10 Is Critical for the Progression and Maintenance of Depigmentation in a Mouse Model of Vitiligo

Mehdi Rashighi, Priti Agarwal, Jillian M. Richmond, Tajie H. Harris, Karen Dresser, Ming-Wan Su, Youwen Zhou, April Deng, Christopher A. Hunter, Andrew D. Luster, John E. Harris*

*Corresponding author. E-mail: john.harris@umassmed.edu

Published 12 February 2014, Sci. Transl. Med. 6, 223ra23 (2014)
DOI: 10.1126/scitranslmed.3007811

This PDF file includes:

  • Fig. S1. Validation of selected transcripts in humans and mice.
  • Fig. S2. Frequencies of melanocyte antigen–specific T cells in peripheral blood of healthy or vitiligo patients.
  • Fig. S3. Staining controls for vitiligo biopsy immunohistochemistry.
  • Fig. S4. Gating strategy for examining CXCR3+ mouse T cells.
  • Fig. S5. Cotransfers of wild-type and CXCR3-deficient PMELs.
  • Fig. S6. Repigmentation after treatment with CXCL10-neutralizing antibody but not isotype control antibody.
  • Table S1. Percentages of CXCR3+ and CXCR3 PMELs in vitiligo mice, gated on total CD8+ cells.

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