Supplementary Materials

Supplementary Material for:

A Factor XIIa Inhibitory Antibody Provides Thromboprotection in Extracorporeal Circulation Without Increasing Bleeding Risk

Magnus Larsson, Veronika Rayzman, Marc W. Nolte, Katrin F. Nickel, Jenny Björkqvist, Anne Jämsä, Matthew P. Hardy, Marion Fries, Stefan Schmidbauer, Patricia Hedenqvist, Michael Broomé, Ingo Pragst, Gerhard Dickneite, Michael J. Wilson, Andrew D. Nash, Con Panousis, Thomas Renné*

*Corresponding author. E-mail:

Published 5 February 2014, Sci. Transl. Med.6, 222ra17 (2014)
DOI: 10.1126/scitranslmed.3006804

This PDF file includes:

  • Table S1. Clinical chemistry biomarkers during ECMO.
  • Fig. S1. 3F7 binding characteristics.
  • Fig. S2. Interference of 3F7 with FXIIa-driven contact system activation in plasma.
  • Fig. S3. NETs and leukocytes in thrombi generated under flow.
  • Materials and Methods
  • References (6165)

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