Supplementary Materials

Supplementary Material for:

Therapeutic Inflammatory Monocyte Modulation Using Immune-Modifying Microparticles

Daniel R. Getts,* Rachael L. Terry, Meghann Teague Getts, Celine Deffrasnes, Marcus Müller, Caryn van Vreden, Thomas M. Ashhurst, Belal Chami, Derrick McCarthy, Huiling Wu, Jin Ma, Aaron Martin, Lonnie D. Shae, Paul Witting, Geoffrey S. Kansas, Joachim Kühn, Wali Hafezi, Iain L. Campbell, David Reilly, Jana Say, Louise Brown, Melanie Y. White, Stuart J. Cordwell, Steven J. Chadban, Edward B. Thorp, Shisan Bao, Stephen D. Miller,* Nicholas J. C. King*

*Corresponding author. E-mail: (D.R.G.); (S.D.M.); (N.J.C.K.)

Published 15 January 2014, Sci. Transl. Med. 6, 219ra7 (2014)
DOI: 10.1126/scitranslmed.3007563

This PDF file includes:

  • Materials and Methods
  • Fig. S1. PS-IMPs reduce cytokine and chemokine production in the WNVinfected brain.
  • Fig. S2. IMP clearance kinetics, lack of IMP localization to the brain, and PLGAIMP treatment in TG peritonitis.
  • Fig. S3. IMP localization and marginal zone macrophage depletion.
  • Table S1. Particle physical properties.
  • Table S2. Opsonized proteins found on IMP.

[Download PDF]