Supplementary Materials

Supplementary Material for:

Silencing HoxA1 by Intraductal Injection of siRNA Lipidoid Nanoparticles Prevents Mammary Tumor Progression in Mice

Amy Brock, Silva Krause, Hu Li, Marek Kowalski, Michael S. Goldberg, James J. Collins, Donald E. Ingber*

*Corresponding author. E-mail:

Published 1 January 2014, Sci. Transl. Med. 6, 217ra2 (2014)
DOI: 10.1126/scitranslmed.3007048

This PDF file includes:

  • Materials and Methods
  • Fig. S1. Conventional bioinformatics analysis of mammary gland gene expression changes in C3(1)-SV40Tag–driven tumorigenesis.
  • Fig. S2. Silencing of HoxA1 in human cell lines in vitro.
  • Fig. S3. In vivo delivery of siRNA to the mammary ductal tree.
  • Fig. S4. Monitoring systemic response to in vivo RNAi.

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