Supplementary Materials

Supplementary Material for:

Real-Time, Aptamer-Based Tracking of Circulating Therapeutic Agents in Living Animals

Brian Scott Ferguson, David A. Hoggarth, Dan Maliniak, Kyle Ploense, Ryan J. White, Nick Woodward, Kuangwen Hsieh, Andrew J. Bonham, Michael Eisenstein, Tod E. Kippin, Kevin W. Plaxco, Hyongsok Tom Soh*

*Corresponding author. E-mail: tsoh{at}

Published 27 November 2013, Sci. Transl. Med. 5, 213ra165 (2013)
DOI: 10.1126/scitranslmed.3007095

This PDF file includes:

  • Fig. S1. Device architecture and fabrication.
  • Fig. S2. Confocal analysis of human whole blood in MEDIC channel.
  • Fig. S3. Finite element model of diffusive transport of target in the MEDIC channel.
  • Fig. S4. Schematic illustration of SWV.
  • Fig. S5. KDM characterization.
  • Fig. S6. DOX a-phase half-life measurement in a cohort of rats.
  • Fig. S7. Analyte dose responses in human whole blood in MEDIC chip.

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