Supplementary Materials

Supplementary Material for:

Immune-Mediated Pore-Forming Pathways Induce Cellular Hypercitrullination and Generate Citrullinated Autoantigens in Rheumatoid Arthritis

Violeta Romero, Justyna Fert-Bober, Peter A. Nigrovic, Erika Darrah, Uzma J. Haque, David M. Lee, Jennifer van Eyk, Antony Rosen, Felipe Andrade*

*Corresponding author. E-mail:

Published 30 October 2013, Sci. Transl. Med. 5, 209ra150 (2013)
DOI: 10.1126/scitranslmed.3006869

This PDF file includes:

  • Fig. S1. 293T cells have no PAD expression or citrullination activity.
  • Fig. S2. Expression of cytotoxic cell markers and cleaved BID/caspase-3 in RA SF cells.
  • Table S1. Patient demographics and laboratory values.

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Other Supplementary Material for this manuscript includes the following:

  • Table S2 (Microsoft Excel format). Identity of citrullinated proteins in RA SF cells and neutrophils incubated in the absence (control) or presence of perforin or complement using mass spectrometry.

[Table S2]