Supplementary Materials

Supplementary Material for:

Postnatal Soluble FGFR3 Therapy Rescues Achondroplasia Symptoms and Restores Bone Growth in Mice

Stéphanie Garcia, Béatrice Dirat, Thomas Tognacci, Nathalie Rochet, Xavier Mouska, Stéphanie Bonnafous, Stéphanie Patouraux, Albert Tran, Philippe Gual, Yannick Le Marchand-Brustel, Isabelle Gennero, Elvire Gouze*

*Corresponding author. E-mail:

Published 18 September 2013, Sci. Transl. Med. 5, 203ra124 (2013)
DOI: 10.1126/scitranslmed.3006247

This PDF file includes:

  • Methods
  • Fig. S1. Representative x-ray radiographs of skeletons of Fgfr3ach/+ and wild-type mice treated with vehicle or sFGFR3.
  • Fig. S2. μCT analysis of femoral bone structures after sFGFR3 treatment.
  • Fig. S3. Histological evaluation of the organs after sFGFR3 treatment.
  • Table S1. Body measurements in the different treatment groups.
  • Table S2. Coefficient correlation (r) between organ and body weight in the different treatment groups.
  • Table S3. Blood biochemistry was unchanged by sFGFR3 treatment.
  • Table S4. Blood counts were not modified by sFGFR3 treatment.
  • Table S5. Blood counts were not modified 8 months after sFGFR3 treatment.

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