Supplementary Materials

Supplementary Material for:

Productive Replication of Ebola Virus Is Regulated by the c-Abl1 Tyrosine Kinase

Mayra GarcĂ­a, Arik Cooper, Wei Shi, William Bornmann, Ricardo Carrion, Daniel Kalman, Gary J. Nabel*

*To whom correspondence should be addressed. E-mail: gnabel{at}

Published 29 February 2012, Sci. Transl. Med. 4, 123ra24 (2012)
DOI: 10.1126/scitranslmed.3003500

This PDF file includes:

  • Fig. S1. Transient transfection of NP, VP40, VP35, VP24, and GP gives rise to Ebola VLPs in 293T cells.
  • Fig. S2. GP levels in 293T cell lysates after drug treatment.
  • Fig. S3. Tyrosine phosphorylation of c-Abl1 and VP40 after expression of c-Abl1 in 293T cells.
  • Fig. S4. Analysis of VP40 modification in transfected 293T cells.
  • Fig. S5. Nedd4 and c-Abl1 interaction with VP40.
  • Fig. S6. Infection assays.

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