Supplementary Material

Supplementary Material for:

Cholesterol Oxidation Products Are Sensitive and Specific Blood-Based Biomarkers for Niemann-Pick C1 Disease

Forbes D. Porter, David E. Scherrer, Michael H. Lanier, S. Joshua Langmade, Vasumathi Molugu, Sarah E. Gale, Dana Olzeski, Rohini Sidhu, Dennis J. Dietzen, Rao Fu, Christopher A. Wassif, Nicole M. Yanjanin, Steven P. Marso, John House, Charles Vite, Jean E. Schaffer, Daniel S. Ory*

*To whom correspondence should be addressed. E-mail: dory{at}

Published 3 November 2010, Sci. Transl. Med. 2, 56ra81 (2010)
DOI: 10.1126/scitranslmed.3001417

This PDF file includes:

  • Table S1. Plasma oxysterols in NPC1 subjects.
  • Fig. S1. Absence of association of plasma oxysterols with plasma cholesterol or antioxidant capacity.
  • Fig. S2. Free cholesterol concentrations and LDL-stimulated cholesterol esterification in skin fibroblasts from NPC1 subjects.

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