Research ArticleNeuroscience
Hippocampal extracellular matrix alterations contribute to cognitive impairment associated with a chronic depressive-like state in rats
- View ORCID ProfileDanai Riga1,
- View ORCID ProfileIoannis Kramvis2,*,
- View ORCID ProfileMaija K. Koskinen1,*,
- View ORCID ProfilePieter van Bokhoven1,*,
- Johanneke E. van der Harst3,4,
- Tim S. Heistek2,
- A. Jaap Timmerman2,
- View ORCID ProfilePim van Nierop1,
- Roel C. van der Schors1,
- Anton W. Pieneman1,
- Anouk de Weger1,
- Yvar van Mourik5,
- View ORCID ProfileAnton N. M. Schoffelmeer5,
- View ORCID ProfileHuib D. Mansvelder2,
- View ORCID ProfileRhiannon M. Meredith2,
- Witte J. G. Hoogendijk6,
- August B. Smit1,† and
- View ORCID ProfileSabine Spijker1,†,‡
- 1Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
- 2Department of Integrative Neurophysiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
- 3Department of Biology, Institute of Environmental Biology, Animal Ecology group Biology, Utrecht University, Utrecht, Netherlands.
- 4Department of Cognitive Neuroscience, Radboud University Medical Center, Nijmegen, Netherlands.
- 5Department of Anatomy and Neurosciences, Amsterdam Neuroscience, VU Medical Center, Amsterdam, Netherlands.
- 6Department of Psychiatry, Erasmus Medical Center, Rotterdam, Netherlands.
- ↵‡Corresponding author. Email: s.spijker{at}vu.nl
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Science Translational Medicine 20 Dec 2017:
Vol. 9, Issue 421, eaai8753
DOI: 10.1126/scitranslmed.aai8753
Vol. 9, Issue 421, eaai8753
DOI: 10.1126/scitranslmed.aai8753
Danai Riga
1Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Ioannis Kramvis
2Department of Integrative Neurophysiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Maija K. Koskinen
1Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Pieter van Bokhoven
1Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Johanneke E. van der Harst
3Department of Biology, Institute of Environmental Biology, Animal Ecology group Biology, Utrecht University, Utrecht, Netherlands.
4Department of Cognitive Neuroscience, Radboud University Medical Center, Nijmegen, Netherlands.
Tim S. Heistek
2Department of Integrative Neurophysiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
A. Jaap Timmerman
2Department of Integrative Neurophysiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Pim van Nierop
1Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Roel C. van der Schors
1Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Anton W. Pieneman
1Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Anouk de Weger
1Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Yvar van Mourik
5Department of Anatomy and Neurosciences, Amsterdam Neuroscience, VU Medical Center, Amsterdam, Netherlands.
Anton N. M. Schoffelmeer
5Department of Anatomy and Neurosciences, Amsterdam Neuroscience, VU Medical Center, Amsterdam, Netherlands.
Huib D. Mansvelder
2Department of Integrative Neurophysiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Rhiannon M. Meredith
2Department of Integrative Neurophysiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Witte J. G. Hoogendijk
6Department of Psychiatry, Erasmus Medical Center, Rotterdam, Netherlands.
August B. Smit
1Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Sabine Spijker
1Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
