15 November 2017
Vol 9, Issue 416

About The Cover

Cover image expansion

ONLINE COVER Lung Cancer Drives Pulmonary Hypertension. This image shows a ring of lung cancer cells and interspersed immune cells surrounding a blood vessel. Pullamsetti et al. discovered that lung cancer can induce pulmonary hypertension through inflammation-enhancing cross-talk between the cancer cells and immune cells in the tumor microenvironment, which may explain some of the clinical symptoms seen in lung cancer patients, such as shortness of breath. [CREDIT: RAJKUMAR SAVAI/MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH]