Research ArticleCancer

Aristolochic acids and their derivatives are widely implicated in liver cancers in Taiwan and throughout Asia

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Science Translational Medicine  18 Oct 2017:
Vol. 9, Issue 412, eaan6446
DOI: 10.1126/scitranslmed.aan6446

Article Information

vol. 9 no. 412

PubMed: 
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History: 
  • Received for publication May 12, 2017
  • Resubmitted July 31, 2017
  • Accepted for publication September 25, 2017
  • .

Author Information

  1. Alvin W. T. Ng1,2,3,*,
  2. Song Ling Poon4,*,
  3. Mi Ni Huang1,2,
  4. Jing Quan Lim4,5,
  5. Arnoud Boot1,2,
  6. Willie Yu1,2,
  7. Yuka Suzuki1,2,
  8. Saranya Thangaraju4,
  9. Cedric C. Y. Ng4,
  10. Patrick Tan2,6,7,8,
  11. See-Tong Pang9,
  12. Hao-Yi Huang10,
  13. Ming-Chin Yu11,
  14. Po-Huang Lee12,
  15. Sen-Yung Hsieh10,,
  16. Alex Y. Chang13,,
  17. Bin T. Teh2,4,7,14, and
  18. Steven G. Rozen1,2,3,7,
  1. 1Centre for Computational Biology, Duke-NUS Medical School, Singapore 169857, Singapore.
  2. 2Programme in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore 169857, Singapore.
  3. 3NUS Graduate School for Integrative Sciences and Engineering, Singapore 117456, Singapore.
  4. 4Laboratory of Cancer Epigenome, Division of Medical Science, National Cancer Centre Singapore, Singapore 169610, Singapore.
  5. 5Lymphoma Genomic Translational Research Laboratory, Division of Medical Oncology, National Cancer Centre Singapore, Singapore 169610, Singapore.
  6. 6Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.
  7. 7SingHealth/Duke-NUS Precision Medicine Institute, Singapore 169609, Singapore.
  8. 8Genome Institute of Singapore, Singapore 138672, Singapore.
  9. 9Division of Urooncology, Department of Urology, Chang Gung University and Memorial Hospital, Linkou, Taoyuan 33305, Taiwan.
  10. 10Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Linkou, Taoyuan 33305, Taiwan.
  11. 11Department of General Surgery, Chang Gung Memorial Hospital, Linkou, Taoyuan 33305, Taiwan.
  12. 12Department of Surgery, National Taiwan University, Taipei 10051, Taiwan.
  13. 13Johns Hopkins Singapore, Singapore 308433, Singapore.
  14. 14Institute of Molecular and Cell Biology, Singapore 138673, Singapore.
  1. Corresponding author. Email: siming.shia{at}msa.hinet.net (S.-Y.H.); alexchang{at}imc.jhmi.edu (A.Y.C.); teh.bin.tean{at}singhealth.com.sg (B.T.T.); steve.rozen{at}duke-nus.edu.sg (S.G.R.)
    • * These authors contributed equally to this work.

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