Research ArticleInfluenza

A multimechanistic antibody targeting the receptor binding site potently cross-protects against influenza B viruses

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Science Translational Medicine  18 Oct 2017:
Vol. 9, Issue 412, eaam5752
DOI: 10.1126/scitranslmed.aam5752

Article Information

vol. 9 no. 412

PubMed: 
Print ISSN: 
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History: 
  • Received for publication December 11, 2016
  • Resubmitted May 16, 2017
  • Accepted for publication September 5, 2017

Author Information

  1. Chenguang Shen1,*,
  2. Junyu Chen1,*,
  3. Rui Li1,*,
  4. Mengya Zhang1,*,
  5. Guosong Wang1,*,
  6. Svetlana Stegalkina2,
  7. Limin Zhang1,
  8. Jing Chen1,
  9. Jianli Cao1,
  10. Xingjian Bi1,
  11. Stephen F. Anderson2,
  12. Timothy Alefantis2,
  13. Minwei Zhang3,
  14. Xiaoyang Cai3,
  15. Kunyu Yang4,
  16. Qingbing Zheng1,
  17. Mujing Fang1,
  18. Hai Yu1,
  19. Wenxin Luo1,
  20. Zizheng Zheng1,
  21. Quan Yuan1,
  22. Jun Zhang1,
  23. James Wai-Kuo Shih1,
  24. Harry Kleanthous2,
  25. Honglin Chen1,5,
  26. Yixin Chen1, and
  27. Ningshao Xia1,
  1. 1State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, School of Public Health, Xiamen University, Xiamen 361102, Fujian, China.
  2. 2Sanofi Pasteur, Cambridge, MA 02139, USA.
  3. 3Department of Emergency and Critical Care Medicine, First Affiliated Hospital of Xiamen University, Xiamen 361002, Fujian, China.
  4. 4Xiamen International Travel Healthcare Center, Xiamen 361012, Fujian, China.
  5. 5Department of Microbiology, State Key Laboratory of Emerging Infectious Diseases, University of Hong Kong, Hong Kong, China.
  1. Corresponding author. Email: yxchen2008{at}xmu.edu.cn (Y.C.); nsxia{at}xmu.edu.cn (N.X.)
    • * These authors contributed equally to this work.

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