Editors' ChoiceGenome Editing

Check twice, cut once—Improved CRISPR-Cas9 genome editing accuracy

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Science Translational Medicine  11 Oct 2017:
Vol. 9, Issue 411, eaap8165
DOI: 10.1126/scitranslmed.aap8165


Based on observations of the mechanism underlying target discrimination, researchers have developed highly accurate variants of CRISPR-Cas9.

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