Research ArticleCARDIAC IMAGING
Responsive monitoring of mitochondrial redox states in heart muscle predicts impending cardiac arrest
- View ORCID ProfileDorothy A. Perry1,2,*,
- View ORCID ProfileJoshua W. Salvin1,2,*,
- View ORCID ProfilePadraic Romfh3,
- Peili Chen3,
- Kalyani Krishnamurthy3,
- Lindsay M. Thomson1,
- Brian D. Polizzotti1,2,
- View ORCID ProfileFrancis X. McGowan4,5,
- View ORCID ProfileDaryoosh Vakhshoori3,† and
- View ORCID ProfileJohn N. Kheir1,2,†
- 1Department of Cardiology, Boston Children’s Hospital, Boston, MA 02115, USA.
- 2Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA.
- 3Pendar Technologies, Cambridge, MA 02138, USA.
- 4Department of Anesthesiology and Critical Care Medicine, Children’s Hospital of Philadelphia, PA 19104, USA.
- 5Department of Anesthesiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
- ↵†Corresponding author. Email: dvakhshoori{at}pendar.tech (D.V.); john.kheir{at}childrens.harvard.edu (J.N.K.)
↵* These authors contributed equally to this work.
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Science Translational Medicine 20 Sep 2017:
Vol. 9, Issue 408, eaan0117
DOI: 10.1126/scitranslmed.aan0117
Vol. 9, Issue 408, eaan0117
DOI: 10.1126/scitranslmed.aan0117
Dorothy A. Perry
1Department of Cardiology, Boston Children’s Hospital, Boston, MA 02115, USA.
2Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA.
Joshua W. Salvin
1Department of Cardiology, Boston Children’s Hospital, Boston, MA 02115, USA.
2Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA.
Padraic Romfh
3Pendar Technologies, Cambridge, MA 02138, USA.
Peili Chen
3Pendar Technologies, Cambridge, MA 02138, USA.
Kalyani Krishnamurthy
3Pendar Technologies, Cambridge, MA 02138, USA.
Lindsay M. Thomson
1Department of Cardiology, Boston Children’s Hospital, Boston, MA 02115, USA.
Brian D. Polizzotti
1Department of Cardiology, Boston Children’s Hospital, Boston, MA 02115, USA.
2Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA.
Francis X. McGowan
4Department of Anesthesiology and Critical Care Medicine, Children’s Hospital of Philadelphia, PA 19104, USA.
5Department of Anesthesiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Daryoosh Vakhshoori
3Pendar Technologies, Cambridge, MA 02138, USA.
John N. Kheir
1Department of Cardiology, Boston Children’s Hospital, Boston, MA 02115, USA.
2Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA.