13 September 2017
Vol 9, Issue 407

About The Cover

Cover image expansion

ONLINE COVER Just Apelin-g Around. Apelin is a naturally occurring peptide which blocks the uptake of fatty acids from the blood and thereby slows the development of conditions such as diabetes and atherosclerosis. This image shows the distribution of apelin (green) in the white adipose tissue, demonstrating its localization in endothelial cells (red), while cell nuclei are highlighted in blue. Hwangbo et al. investigated the mechanism of action of apelin and discovered a drug that can mimic its function and thereby promote metabolic health in a mouse model. [CREDIT: B. SHARMA/YALE SCHOOL OF MEDICINE]