06 September 2017
Vol 9, Issue 406

About The Cover

Cover image expansion

ONLINE COVER The Write Tool for the Job. To rapidly identify cancerous tissue in situ, Zhang et al. developed the MasSpec Pen, shown here in simulation. The handheld device uses a small volume water droplet to pick up molecules from the tissue surface (see inset) and transports the droplet to an attached mass spectrometer, where the molecules are analyzed. The device distinguished healthy human tissues from cancerous specimens, and identified tumors in mice when used intraoperatively. This mighty pen offers surgeons a nondestructive tool to add to their arsenal to distinguish healthy from tumor tissue. [CREDIT: LIVIA S. EBERLIN, JIALING ZHANG, NOAH GIESE/THE UNIVERSITY OF TEXAS AT AUSTIN]