09 August 2017
Vol 9, Issue 402

About The Cover

Cover image expansion

ONLINE COVER Saving Bone Marrow from Friendly Fire. Chemotherapy has saved the lives of numerous cancer patients over the last several decades and continues to be widely used today, as illustrated in this image, but, unfortunately, it is not a benign treatment. Standard chemotherapy drugs indiscriminately kill all proliferating cells, including those in the bone marrow. Now, Taylor et al. report that quizartinib, a drug that is already being developed for use in some cancers, can be carefully timed with chemotherapy to induce quiescence of healthy bone marrow cells and protect them from dying without impairing the treatment's antitumor efficacy. [CREDIT: THE IMAGE BANK]