02 August 2017
Vol 9, Issue 401

About The Cover

Cover image expansion

ONLINE COVER Taming of the TH2. Although scientists have known for a long time that helper T type 2 (TH2) cells are implicated in allergic responses, it is difficult to distinguish harmful TH2 cells from those that fight pathogens. Wambre et al. detected a subset of TH2 cells only in allergic individuals, like the girl pictured here, and saw this subset decrease in patients responding to immunotherapy. As Cousins discusses in the accompanying Focus article, these findings not only pave the way for more accurate studies of allergy pathogenesis, but also suggest that this subset could be specifically targeted for therapy. [CREDIT: SKYNESHER/ISTOCKPHOTO]