Research ArticleEMERGING INFECTIONS

Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses

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Science Translational Medicine  28 Jun 2017:
Vol. 9, Issue 396, eaal3653
DOI: 10.1126/scitranslmed.aal3653

Article Information

vol. 9 no. 396

PubMed: 
Print ISSN: 
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History: 
  • Received for publication November 8, 2016
  • Accepted for publication May 17, 2017
  • .

Author Information

  1. Timothy P. Sheahan1,*,
  2. Amy C. Sims1,*,
  3. Rachel L. Graham1,
  4. Vineet D. Menachery1,
  5. Lisa E. Gralinski1,
  6. James B. Case2,
  7. Sarah R. Leist1,
  8. Krzysztof Pyrc3,
  9. Joy Y. Feng4,
  10. Iva Trantcheva4,
  11. Roy Bannister4,
  12. Yeojin Park4,
  13. Darius Babusis4,
  14. Michael O. Clarke4,
  15. Richard L. Mackman4,
  16. Jamie E. Spahn4,
  17. Christopher A. Palmiotti4,
  18. Dustin Siegel4,
  19. Adrian S. Ray4,
  20. Tomas Cihlar4,
  21. Robert Jordan4,
  22. Mark R. Denison5, and
  23. Ralph S. Baric1,
  1. 1Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  2. 2Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  3. 3Department of Microbiology, Faculty of Biochemistry, Biophysics, and Biotechnology, Jagiellonian University, Krakow, Poland.
  4. 4Gilead Sciences Inc., Foster City, CA 94404, USA.
  5. 5Division of Infectious Diseases, Department of Pediatrics and Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  1. Corresponding author. Email: mark.denison{at}vanderbilt.edu (M.R.D.); rbaric{at}email.unc.edu (R.S.B.)
    • * These authors contributed equally to this work.

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