Research ArticleDiabetes
Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetes
- Annika S. Axelsson1,
- Emily Tubbs1,
- Brig Mecham2,
- Shaji Chacko3,
- Hannah A. Nenonen1,
- Yunzhao Tang1,
- Jed W. Fahey4,
- Jonathan M. J. Derry5,
- Claes B. Wollheim1,6,
- Nils Wierup1,
- Morey W. Haymond3,
- Stephen H. Friend5,
- Hindrik Mulder1 and
- Anders H. Rosengren1,5,7,*
- 1Department of Clinical Sciences, Lund University Diabetes Center, Malmö, SE-20502 Malmö, Sweden.
- 2Trialomics, Seattle, WA 98115, USA.
- 3U.S. Department of Agriculture/Agricultural Research Service, Children’s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
- 4Departments of Medicine, Pharmacology and Molecular Sciences, and International Health, and Cullman Chemoprotection Center, Johns Hopkins University, Baltimore, MD 21205, USA.
- 5Sage Bionetworks, 1100 Fairview Avenue North, Seattle, WA 98109, USA.
- 6Department of Cell Physiology and Metabolism, University Medical Center, CH-1211 Geneva, Switzerland.
- 7Institute of Neuroscience and Physiology, University of Gothenburg, SE-40530 Göteborg, Sweden.
- ↵*Corresponding author. Email: anders.rosengren{at}gu.se
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Science Translational Medicine 14 Jun 2017:
Vol. 9, Issue 394, eaah4477
DOI: 10.1126/scitranslmed.aah4477