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Research ArticleVaccines
Vaccine priming is restricted to draining lymph nodes and controlled by adjuvant-mediated antigen uptake
- View ORCID ProfileFrank Liang1,2,
- View ORCID ProfileGustaf Lindgren1,2,
- Kerrie J. Sandgren1,*,
- Elizabeth A. Thompson1,2,
- Joseph R. Francica3,
- View ORCID ProfileAnja Seubert4,
- Ennio De Gregorio4,
- Susan Barnett5,†,
- Derek T. O’Hagan5,
- Nancy J. Sullivan3,
- Richard A. Koup3,
- Robert A. Seder3 and
- View ORCID ProfileKarin Loré1,2,‡
- 1Immunology and Allergy Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
- 2Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
- 3Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
- 4GSK Vaccines, Siena, Italy.
- 5GSK Vaccines, Rockville, MD 20850, USA.
- ↵‡Corresponding author. Email: karin.lore{at}ki.se
See allHide authors and affiliations
Science Translational Medicine 07 Jun 2017:
Vol. 9, Issue 393, eaal2094
DOI: 10.1126/scitranslmed.aal2094
Vol. 9, Issue 393, eaal2094
DOI: 10.1126/scitranslmed.aal2094
Frank Liang
1Immunology and Allergy Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
2Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
Gustaf Lindgren
1Immunology and Allergy Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
2Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
Kerrie J. Sandgren
1Immunology and Allergy Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
Elizabeth A. Thompson
1Immunology and Allergy Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
2Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
Joseph R. Francica
3Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Anja Seubert
4GSK Vaccines, Siena, Italy.
Ennio De Gregorio
4GSK Vaccines, Siena, Italy.
Susan Barnett
5GSK Vaccines, Rockville, MD 20850, USA.
Derek T. O’Hagan
5GSK Vaccines, Rockville, MD 20850, USA.
Nancy J. Sullivan
3Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Richard A. Koup
3Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Robert A. Seder
3Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Karin Loré
1Immunology and Allergy Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
2Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
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