Editors' ChoiceIMMUNE DEFENSE

When TLRs fail, IgG has your back

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Science Translational Medicine  22 Mar 2017:
Vol. 9, Issue 382, eaan0768
DOI: 10.1126/scitranslmed.aan0768

Abstract

Inherited TIRAP deficiency confers susceptibility to staphylococcal disease via impaired TLR2 and TLR4 responses, which can be rescued by bacteria-specific antibodies.

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