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Research ArticleInfectious Disease
Bacterial virulence phenotypes of Escherichia coli and host susceptibility determine risk for urinary tract infections
- View ORCID ProfileHenry L. Schreiber IV1,2,
- View ORCID ProfileMatt S. Conover1,
- View ORCID ProfileWen-Chi Chou2,
- View ORCID ProfileMichael E. Hibbing1,
- View ORCID ProfileAbigail L. Manson2,
- Karen W. Dodson1,
- View ORCID ProfileThomas J. Hannan3,
- Pacita L. Roberts4,
- View ORCID ProfileAnn E. Stapleton4,
- View ORCID ProfileThomas M. Hooton5,
- View ORCID ProfileJonathan Livny2,*,
- View ORCID ProfileAshlee M. Earl2,* and
- View ORCID ProfileScott J. Hultgren1,6,*
- 1Department of Molecular Microbiology, Washington University, St. Louis, MO 63110, USA.
- 2Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA.
- 3Department of Pathology and Immunology, Washington University, St. Louis, MO 63110, USA.
- 4Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA 98195, USA.
- 5Division of Infectious Diseases, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
- 6Center for Women’s Infectious Disease Research, Washington University, St. Louis, MO 63110, USA.
- ↵*Corresponding author. Email: livny{at}broadinstitute.org (J.L.); aearl{at}broadinstitute.org (A.M.E.); hultgren{at}wusm.wustl.edu (S.J.H.)
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Science Translational Medicine 22 Mar 2017:
Vol. 9, Issue 382, eaaf1283
DOI: 10.1126/scitranslmed.aaf1283
Vol. 9, Issue 382, eaaf1283
DOI: 10.1126/scitranslmed.aaf1283
Henry L. Schreiber IV
1Department of Molecular Microbiology, Washington University, St. Louis, MO 63110, USA.
2Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA.
Matt S. Conover
1Department of Molecular Microbiology, Washington University, St. Louis, MO 63110, USA.
Wen-Chi Chou
2Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA.
Michael E. Hibbing
1Department of Molecular Microbiology, Washington University, St. Louis, MO 63110, USA.
Abigail L. Manson
2Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA.
Karen W. Dodson
1Department of Molecular Microbiology, Washington University, St. Louis, MO 63110, USA.
Thomas J. Hannan
3Department of Pathology and Immunology, Washington University, St. Louis, MO 63110, USA.
Pacita L. Roberts
4Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA 98195, USA.
Ann E. Stapleton
4Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA 98195, USA.
Thomas M. Hooton
5Division of Infectious Diseases, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Jonathan Livny
2Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA.
Ashlee M. Earl
2Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA.
Scott J. Hultgren
1Department of Molecular Microbiology, Washington University, St. Louis, MO 63110, USA.
6Center for Women’s Infectious Disease Research, Washington University, St. Louis, MO 63110, USA.
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