Research ArticleCancer

Antagonism of EGFR and Notch limits resistance to EGFR inhibitors and radiation by decreasing tumor-initiating cell frequency

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Science Translational Medicine  08 Mar 2017:
Vol. 9, Issue 380, eaag0339
DOI: 10.1126/scitranslmed.aag0339

Article Information

vol. 9 no. 380

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication May 3, 2016
  • Resubmitted October 16, 2016
  • Accepted for publication February 11, 2017
  • .

Author Information

  1. Shi Hu1,*,,
  2. Wenyan Fu2,3,,
  3. Tian Li1,
  4. Qingning Yuan1,
  5. Feifei Wang1,
  6. Gaojian Lv1,
  7. Yuanyuan Lv1,
  8. Xiaoyan Fan1,
  9. Yafeng Shen1,
  10. Fangxing Lin1,
  11. Ying Tang1,
  12. Xuting Ye1,
  13. Yongji Yang1 and
  14. Changhai Lei1,*
  1. 1Department of Biophysics, College of Basic Medical Sciences, Second Military Medical University, Shanghai 200433, China.
  2. 2Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200030, China.
  3. 3Department of Breast Surgery, Key Laboratory of Breast Cancer in Shanghai, Collaborative Innovation Center of Cancer Medicine, Fudan University Shanghai Cancer Center, Shanghai 200030, China.
  1. *Corresponding author. Email: hus{at}smmu.edu.cn, hus{at}aftertumor.com (S.H.); lei{at}smmu.edu.cn (C.L.)
    • These authors contributed equally to this work.

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