Research ArticleMicrobiome

IgA-coated E. coli enriched in Crohn’s disease spondyloarthritis promote TH17-dependent inflammation

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Science Translational Medicine  08 Feb 2017:
Vol. 9, Issue 376, eaaf9655
DOI: 10.1126/scitranslmed.aaf9655

Article Information

vol. 9 no. 376

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication May 16, 2016
  • Resubmitted August 12, 2016
  • Accepted for publication December 27, 2016

Author Information

  1. Monica Viladomiu1,*,
  2. Charles Kivolowitz1,*,
  3. Ahmed Abdulhamid1,
  4. Belgin Dogan2,
  5. Daniel Victorio1,
  6. Jim G. Castellanos1,
  7. Viola Woo1,
  8. Fei Teng3,
  9. Nhan L. Tran3,
  10. Andrew Sczesnak4,
  11. Christina Chai1,
  12. Myunghoo Kim5,
  13. Gretchen E. Diehl5,
  14. Nadim J. Ajami5,
  15. Joseph F. Petrosino5,
  16. Xi K. Zhou6,
  17. Sergio Schwartzman7,
  18. Lisa A. Mandl7,
  19. Meira Abramowitz8,
  20. Vinita Jacob8,
  21. Brian Bosworth9,
  22. Adam Steinlauf8,
  23. Ellen J. Scherl8,
  24. Hsin-Jung Joyce Wu3,
  25. Kenneth W. Simpson2 and
  26. Randy S. Longman1,8,
  1. 1Jill Roberts Institute for Research in Inflammatory Bowel Disease (IBD), Weill Cornell Medicine, New York, NY 10021, USA.
  2. 2College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.
  3. 3Department of Immunobiology, University of Arizona, Tucson, AZ 85719, USA.
  4. 4Department of Bioengineering, University of California, Berkeley, Berkeley, CA 94709, USA.
  5. 5Alkek Center for Metagenomics and Microbiome Research, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.
  6. 6Division of Biostatistics and Epidemiology, Weill Cornell Medical College, New York, NY 10065, USA.
  7. 7Hospital for Special Surgery, New York, NY 10021, USA.
  8. 8Jill Roberts Center for IBD, Weill Cornell Medicine, New York, NY 10021, USA.
  9. 9Department of Medicine, New York University School of Medicine, New York, NY 10016, USA.
  1. Corresponding author. Email: ral2006{at}med.cornell.edu
    • * These authors contributed equally to this work.

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